Preparation, structure of the bioactivity of fluoride apatite-bioactive glass 453P4 nano-composite

Document Type: Original Research Paper


1 Department of Engineering, Shahrood Branch, Islamic Azad University, Shahrood, Iran

2 Department of material engineering,faculty of engineering,Islamic azad university Maybod beranch,Iran



This research has been done to study characteristic and biocompatible evaluation of a nano bio composite ceramic with the bioglass as a first phase. In this regard synthesis of this bioglass of 453P4 has been considered as the first phase and flour apatite considered as the second phase. Afterwards, nano composite with the base of bioglass 453P4 has been synthesized by sol-gel method. The synthesized nanoparticles and nanocomposite have been characterized with the help of different techniques, using field emission scanning electron microscope, x-ray powder diffraction, fourier-transform infrared spectroscopy, X-ray fluorescence to evaluate crystal structure, microstructure, and morphology. The results of this section indicated a synthesis of bioglass453P4-fluor apatite nano composite with particle size about of 20-30 nm in crystals for all samples and 70-90% crystallinity . Result of FTIR analyses showed that the purity in the structure of this nano composite .The result of MTT assay indicated nontoxicity and decreased cell viability in 7 days compared with the first day.