Document Type: Original Research Paper
Department of Engineering, Shahrood Branch, Islamic Azad University, Shahrood, Iran
Department of Material Engineering, Maybod Branch, Islamic Azad University, Maybod, Iran
Department of Material Engineering, Yazd Branch, Islamic Azad University, Yazd, Iran
This research has been done to study characteristic and biocompatible evaluation of a nano-biocomposite
ceramic with the bioglass (BG) as a first phase. In this regard, synthesis of S53P4 (53% SiO2, 4% P2O5,
23% Na2O and 20% CaO) bioglass has been considered as the first phase and flourapatite (FA) considered
as the second phase. Afterwards, nanocomposite with the base of S53P4 bioglass has been synthesized
by sol-gel method. The synthesized nanoparticles and nanocomposite have been characterized with the
help of different techniques, using field emission scanning electron microscope (FESEM), X-ray diffraction
(XRD), Fourier transforms infrared spectroscopy (FT-IR), X-ray fluorescence (XRF) to evaluate crystal
structure, microstructure, and morphology. The results showed that the crystallite size and the crystallinity
of S53P4 bioglass-fluorapatite nanocomposites were about 20-30 nm and 70-90%, respectively.
The FT-IR analyses displayed that the purity in the structure of this nanocomposite. The result of MTT
(3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyltetrazolium Bromide) assay indicated the nontoxicity and also
decreasing of cell viability in 7 days compared with the first day.