Mechanical properties improvement and bone regeneration of calcium phosphate bone cement, Polymethyl methacrylate and glass ionomer

Document Type : Original Research Paper


1 Biomedical Engineering Department, Islamic Azad University, Najafabad Branch, Iran

2 Department of Mechanical Engineering, Khomeinishahr branch, Islamic Azad University-Khomeinishahr, Iran

3 Youth and Elite Research Club, Islamic Azad University, Najafabad Branch, Iran



Advancement in nanoscience and biotechnology of bone materials and cement has
been increasing over the past several decades. The combination of biomaterials
with trace elements for bone cement has verified their better mechanical strength
and biocompatibility response. Also, the ionic replacement has affected the
chemical, physical and biological properties of the substance. Pyrophosphate has
supported better absorption of calcium phosphates (CaPs) and bone formation.
Bone cement is the ionomer of an important material in tooth repair application
used in the tooth filling, tooth cover, and to fix adhesions of the tooth and crown.
Nanoparticle additives (magnesium oxide (MgO), hydroxyapatite (HA), chitosan
(CH), barium sulfate and silica) and alternate monomers can be effective with
Polymethyl methacrylate (PMMA) granules and methyl methacrylate monomers
(MMAs) to decrease the isothermal temperature. These materials can be used for
the growth and development of bone cements. This paper aims to demonstrate
a general and different view of the applications of CaP, PMMA, glass ionomer and
bone repair cements in various methods under different experiments procedure